Police said all the arrests are currently being linked.
A number of 'significant' seizures of suspected cocaine were made on Friday (28th May).
Large amounts of cash was also recovered.
Some of the arrests happened on Abbey street and School Walk.
At around 5.30pm, officers arrested a 26-year-old man from the town on suspicion of possession of controlled drugs.
A 58-year-old man was subsequently arrested on Abbey Street on suspicion of possession with intent to supply. Further quantities of suspected cocaine were located on his arrest.
A short time later, officers arrested a 25-year-old man in School Walk, after a significant amount of cash and cocaine were seized from a vehicle. He was arrested on suspicion of possession with intent to supply.
Later that evening, a 54-year-old woman and another 25-year-old man were arrested on suspicion with intent to supply, following a substantial seizure of drugs from a property.
Following interviews, all have been released under investigation.
A Loughborough Business man convicted with two others over PPE Fraud in US
Fire Crews Prevent Wildfire Spread in Normanton
Police Appeal After Indecency Incident in Whitwick
Jeremy Monga leaves Leicester City to complete £10m Manchester City transfer
£1,000 Fine Issued After Fly-Tipping Investigation in Thurmaston
Lioness gets honorary degree in Loughborough
Rapist jailed for 34 years after attack in Loughborough
East Midlands Railway urges essential travel only
