Officers are asking drivers to use different routes.
The A447 between Cadeby and the junction of Bosworth Lane has been closed because of a crash.
Leicestershire Police were called at 9.41 am to a report of a two-vehicle road traffic collision.
Officers are currently at the scene.
UPDATE 13:15
Three people have gone to the hospital a driver in one car and a driver and passenger in another.
A Police Spokesperson said: "None of the injuries are believed to be life-threatening.
"Helimed did attend but they all went by land ambulance. The road remains closed while we await vehicle recovery and clear up."
Fosse 107 will keep this updated when there is more information.
Town Hall reopens after fire
New exhibition shows how BRUSH keeps the lights on
100 years of Shelthorpe estate
Man jailed for 10 years for killing pub-goer
Meet Charnwood's new Mayor
Brothers tried to dupe Leicesteshire Police to avoid jail
Flat Fire in Baxtergate Loughborough
Sir David Attenborough is 100
